"Homoeopathy" was introduced as a medical system of drug therapeutics by a German Physician, Dr. Christian Frederick Samuel Hahnemann in 1805. While translating a medical treatise of Scottish physician and chemist, William Cullen, from English to German, in 1790, Dr Hahnemann came across a foot note under Cinchona that attributed its fever curing property to the astringent (decongestant) qualities of the drug. Being skeptical of Cullen's remarks concerning the effect of Cinchona for curing malaria, Hahnemann experimented its effect on himself by taking repeated doses of cinchona tincture. He experienced fever, shivering and joint pains: symptoms similar to those of malarial fever. After series of experiments, Hahnemann concluded that a drug that could produce certain symptoms in healthy individuals could also cure similar disease symptoms of natural diseases. This was in accordance with some hidden, natural laws of similars as had been vaguely perceived by ancient physicians. This led to the coining of the word "homoeo-pathy" (which comes from the Greek: ὅμοιος hómoios, "-like" and πάθος páthos, "suffering"). Based on this, Hahnemann postulated the key principle of Homoeopathy, the Law of Similars, logically evolving it as an experimental science, according to the method of inductive reasoning after exact observation, correct interpretation, rational explanation and scientific construction. He further studied and experimented his theory, added eight other principles to this key concept and published his works in 1805 called Fragmenta de viribus medicamentorum: positivis sive in sano corpore humano observatis (Fragmentary Observations relative to the Positive Powers of Medicines on the healthy Human Body).
The first volume of this book contains detailed symptoms caused by 27 different drugs. The second volume contains the totality of the symptoms in alphabetical order, which formed the basis of Homeopathic Repertory in later years.